Human Chorionic Gonadotropin
Product Specification:
Human Chorionic Gonadotropin is sialoglycoprotein secreted by the trophoblastic cells of the placenta. The molecule is made of two subunits. The alpha subunit is similar to those of LH, FSH, and TSH. The beta subunit is different from the other hormones and confers its biochemical specificity. HCG maintains the corpus luteum. HCG is available as whole molecule standard (50%) and high purity (95%) grades, or as alpha and beta subunits.
General Information:
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Molecular Weight: 36,700 Daltons alpha-14,500 beta-22,200
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Source: Human Pregnancy Urine
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IU/mg Standard grade 5,000 IU/mg
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IU/mg High Purity 9,000 IU/mg
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Form: lyophilized powder
Storage - 20 degrees C
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Stability: 5 years from date of manufacture
Method of Analysis:
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Purity is determined by SDS-Page.
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Acceptable level Standard grade: 50%
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Acceptable level High purity: 95%
Activity is determined by one of the following methods:
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Method DPC Immulite 1000
Reference Preparation WHO 3rd IS (75/537)
Contaminants Tested:
Contaminant |
Method |
Acceptable level; Standard Grade | Acceptable level; High Purity |
FSH |
ACS 180 |
Less than 0.2% |
Less than 0.05% |
LH |
ACS 180 |
Less than 0.2% |
Less than 0.2% |
TSH |
ACS 180 |
Less than 0.2% |
Less than 0.05% |
