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Alpha-Fetoprotein

Product Specification:

AFP is a glycoprotein containing about 4% carbohydrate. AFP is produced by the fetal liver and is not normally expressed in adults. Diagnostically, it is a tumor marker for testicular, and hepatocellular cancer. Maternal serum levels are elevated when neural tube defects occur.

General Information:

  • Molecular Weight: 70,000 Daltons

  • Source: Human fetal cord serum

  • IU/mg Standard grade 500 KIU/mg

  • IU/mg High Purity 700 KIU/mg

  • Form: lyophilized powder

  • Storage - 20 degrees C

  • Stability: 5 years from date of manufacture

Method of Analysis:

  • Purity is determined by SDS-Page.

  • Acceptable level Standard grade: 50%

  • Acceptable level High purity: 98%

Activity is determined by one of the following methods:

  • Method ACS 180
    Reference Preparation
    WHO 2nd IRP (72/225)

Contaminants Tested:

Contaminant

Method

Acceptable level; Standard Grade

Acceptable level; High Purity

HSA

SDS Page

Not characterized

Less than 2%

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