FSH Alpha and Beta Subunit
Product Specification:
The alpha and beta subunit of FSH are two dissimilar protein chains that together compose FSH. They are produced by chemically cleaving the whole molecule. The alpha chain is identical to the alpha subunit of hCG, LH, and TSH. The beta subunit gives FSH its distinct biological activity.
General Information:
-
Molecular Weight: alpha- 14,500 beta- 17,200
-
Source: Purified whole FSH (human pituitary)
-
Form: lyophilized powder
-
Storage - 20 degrees C
-
Stability: 5 years from date of manufacture
Method of Analysis:
-
Purity is determined by: SDS-Page.
-
Acceptable level: High purity: 95%
Activity is determined by one of the following methods:
-
Method DPC Immulite 1000
Reference Preparation WHO 2nd IRP (78/549) -
Method ACS 180X
Reference Preparation WHO 2nd IS (94/632)
Contaminants Tested:
Contaminant |
Method |
Acceptable level; High Purity |
whole FSH in beta |
ACS 180 |
Less than 2% |
| whole FSH in alpha |
ACS 180 |
Less than 1% |
| TSH |
ACS 180 |
Less than 0.2% |
LH |
ACS 180 |
Less than 0.2% |
